Arctigenin Isolated from Arctium Lappa L. Inhibits IgE Production
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چکیده
منابع مشابه
Arctigenin: a lignan from Arctium lappa
The title compound {systematic name: (3R-trans)-4-[(3,4-dimethoxy-phen-yl)meth-yl]-3-[(4-hydr-oxy-3-methoxy-phen-yl)meth-yl]-4,5-dihydrofuran-2(3H)-one}, C(21)H(24)O(6), has a dibenz-yl-butyrolactone skeleton. The two aromatic rings are inclined at a dihedral angle of 68.75 (7)° with respect to each other. The lactone ring adopts an envelope conformation. A series of O-H⋯O and C-H⋯O hydrogen bo...
متن کاملArctigenin from Arctium lappa inhibits interleukin-2 and interferon gene expression in primary human T lymphocytes
BACKGROUND Arctium lappa (Niubang), a Chinese herbal medicine, is used to treat tissue inflammation. This study investigates the effects of arctigenin (AC), isolated from A. lappa, on anti-CD3/CD28 Ab-stimulated cell proliferation and cytokine gene expression in primary human T lymphocytes. METHODS Cell proliferation was determined with enzyme immunoassays and the tritiated thymidine uptake m...
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In an effort to search for new cancer-fighting therapeutics, we identified a novel anticancer constituent, Lappaol F, fromplantArctiumLappaL. Lappaol F suppressed cancer cell growth in a timeanddose-dependent manner inhumancancer cell lines of various tissue types.We found thatLappaol F inducedG1 andG2 cell-cycle arrest, which was associated with strong induction of p21 and p27 and reduction of...
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In an effort to search for new cancer-fighting therapeutics, we identified a novel anticancer constituent, Lappaol F, from plant Arctium Lappa L. Lappaol F suppressed cancer cell growth in a time- and dose-dependent manner in human cancer cell lines of various tissue types. We found that Lappaol F induced G(1) and G(2) cell-cycle arrest, which was associated with strong induction of p21 and p27...
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Recently, worldwide dietary reference intakes have been considered an important guideline for public health. Some governments and the World Health Organization (WHO) provide guidelines concerning dietary intake. Although an ingredient may have a history of use as a culinary material, changes in the environment over time suggest that the acceptable maximum intake each of food/culinary material s...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2016
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2015.12.954